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Microbiota and CR jointly regulate the levels of BAs. Gene expression of taurine transporter (TauT) (a), cholesterol 7 α-hydroxylase (Cyp7a1; B), Na + /taurocholate cotransporting polypeptide (Ntcp; C), and cysteine sulfonate decarboxylase (Csd; D) was measured in the mucosa of the ileum. The levels of selected bile acids were measured in the liver (e), plasma (f), mucosa of the ileum (g), and feces (h) applying HPLC-MS/MS. Total BAs content was quantified in the mucosa of the ileum using a commercial kit (i). The ratio of CA to TCA (j), DCA to TDCA (k), and UDCA to TUDCA (l) was calculated based on BAs concentration measured in the ileum. Statistical significance between the experimental groups was evaluated using ANOVA with Bonferroni correction for multiple testing; n = 8; * p < .05. Data are presented as mean±SEM. Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using <t>the</t> <t>MATLAB</t> extension <t>COVAIN</t>
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Microbiota and CR jointly regulate the levels of BAs. Gene expression of taurine transporter (TauT) (a), cholesterol 7 α-hydroxylase (Cyp7a1; B), Na + /taurocholate cotransporting polypeptide (Ntcp; C), and cysteine sulfonate decarboxylase (Csd; D) was measured in the mucosa of the ileum. The levels of selected bile acids were measured in the liver (e), plasma (f), mucosa of the ileum (g), and feces (h) applying HPLC-MS/MS. Total BAs content was quantified in the mucosa of the ileum using a commercial kit (i). The ratio of CA to TCA (j), DCA to TDCA (k), and UDCA to TUDCA (l) was calculated based on BAs concentration measured in the ileum. Statistical significance between the experimental groups was evaluated using ANOVA with Bonferroni correction for multiple testing; n = 8; * p < .05. Data are presented as mean±SEM. Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using <t>the</t> <t>MATLAB</t> extension <t>COVAIN</t>
Matlab Tool Covain, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Microbiota and CR jointly regulate the levels of BAs. Gene expression of taurine transporter (TauT) (a), cholesterol 7 α-hydroxylase (Cyp7a1; B), Na + /taurocholate cotransporting polypeptide (Ntcp; C), and cysteine sulfonate decarboxylase (Csd; D) was measured in the mucosa of the ileum. The levels of selected bile acids were measured in the liver (e), plasma (f), mucosa of the ileum (g), and feces (h) applying HPLC-MS/MS. Total BAs content was quantified in the mucosa of the ileum using a commercial kit (i). The ratio of CA to TCA (j), DCA to TDCA (k), and UDCA to TUDCA (l) was calculated based on BAs concentration measured in the ileum. Statistical significance between the experimental groups was evaluated using ANOVA with Bonferroni correction for multiple testing; n = 8; * p < .05. Data are presented as mean±SEM. Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using <t>the</t> <t>MATLAB</t> extension <t>COVAIN</t>
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Microbiota and CR jointly regulate the levels of BAs. Gene expression of taurine transporter (TauT) (a), cholesterol 7 α-hydroxylase (Cyp7a1; B), Na + /taurocholate cotransporting polypeptide (Ntcp; C), and cysteine sulfonate decarboxylase (Csd; D) was measured in the mucosa of the ileum. The levels of selected bile acids were measured in the liver (e), plasma (f), mucosa of the ileum (g), and feces (h) applying HPLC-MS/MS. Total BAs content was quantified in the mucosa of the ileum using a commercial kit (i). The ratio of CA to TCA (j), DCA to TDCA (k), and UDCA to TUDCA (l) was calculated based on BAs concentration measured in the ileum. Statistical significance between the experimental groups was evaluated using ANOVA with Bonferroni correction for multiple testing; n = 8; * p < .05. Data are presented as mean±SEM. Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using <t>the</t> <t>MATLAB</t> extension <t>COVAIN</t>
R2018b Extension Covain V2019.04, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Bharat Biotech covaxin
Candidate vaccines against SARS-CoV-2 and their stages of development (adapted from WHO draft on vaccine candidates).
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MathWorks Inc tool covain 12-03-22
Candidate vaccines against SARS-CoV-2 and their stages of development (adapted from WHO draft on vaccine candidates).
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Candidate vaccines against SARS-CoV-2 and their stages of development (adapted from WHO draft on vaccine candidates).
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Microbiota and CR jointly regulate the levels of BAs. Gene expression of taurine transporter (TauT) (a), cholesterol 7 α-hydroxylase (Cyp7a1; B), Na + /taurocholate cotransporting polypeptide (Ntcp; C), and cysteine sulfonate decarboxylase (Csd; D) was measured in the mucosa of the ileum. The levels of selected bile acids were measured in the liver (e), plasma (f), mucosa of the ileum (g), and feces (h) applying HPLC-MS/MS. Total BAs content was quantified in the mucosa of the ileum using a commercial kit (i). The ratio of CA to TCA (j), DCA to TDCA (k), and UDCA to TUDCA (l) was calculated based on BAs concentration measured in the ileum. Statistical significance between the experimental groups was evaluated using ANOVA with Bonferroni correction for multiple testing; n = 8; * p < .05. Data are presented as mean±SEM. Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using the MATLAB extension COVAIN

Journal: Gut Microbes

Article Title: Microbial contribution to the caloric restriction-triggered regulation of the intestinal levels of glutathione transferases, taurine, and bile acid

doi: 10.1080/19490976.2021.1992236

Figure Lengend Snippet: Microbiota and CR jointly regulate the levels of BAs. Gene expression of taurine transporter (TauT) (a), cholesterol 7 α-hydroxylase (Cyp7a1; B), Na + /taurocholate cotransporting polypeptide (Ntcp; C), and cysteine sulfonate decarboxylase (Csd; D) was measured in the mucosa of the ileum. The levels of selected bile acids were measured in the liver (e), plasma (f), mucosa of the ileum (g), and feces (h) applying HPLC-MS/MS. Total BAs content was quantified in the mucosa of the ileum using a commercial kit (i). The ratio of CA to TCA (j), DCA to TDCA (k), and UDCA to TUDCA (l) was calculated based on BAs concentration measured in the ileum. Statistical significance between the experimental groups was evaluated using ANOVA with Bonferroni correction for multiple testing; n = 8; * p < .05. Data are presented as mean±SEM. Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using the MATLAB extension COVAIN

Article Snippet: Heatmaps were created by using Z-Scored data, showing the relative deviation from the groups’ mean value, and visualized by using the MATLAB extension COVAIN Concerning BAs, CR consistently increased levels of the measured BAs in the liver, plasma, and ileum but much less in the feces ( , Suppl table S1) correspondingly to our previous report.

Techniques: Expressing, Tandem Mass Spectroscopy, Concentration Assay

Candidate vaccines against SARS-CoV-2 and their stages of development (adapted from WHO draft on vaccine candidates).

Journal: Journal of Infection and Public Health

Article Title: Novel corona virus (COVID-19); Global efforts and effective investigational medicines: A review

doi: 10.1016/j.jiph.2021.04.011

Figure Lengend Snippet: Candidate vaccines against SARS-CoV-2 and their stages of development (adapted from WHO draft on vaccine candidates).

Article Snippet: Covaxin Covaxin is developed by Bharat Biotech in association with NIV (National Institute of Virology) at ICMR, Indian Council of Medical Research.

Techniques: Vaccines, Plasmid Preparation, Recombinant, Electroporation, Virus, Clinical Proteomics, Immunopeptidomics, Adjuvant, Infection, Binding Assay, Expressing